NFL Picks Week 4: Patriots vs 49ers

This is a picture of New England Patriots vs San Francisco 49ers for the NFL picks week 4 article preview

The 49ers and the Patriots are set to face off this Sunday at Levi’s Stadium, and with both teams coming off disappointing losses, this matchup is shaping up to be a compelling battle. Which team you will be supporting? In this NFL Picks Week 4: Patriots vs 49ers article, I’ll tell you all the information you need to know about this game.  If you want to place bets on the game check out our sports betting page. (non-Ontario).

New England Patriots vs San Francisco 49ers (Sunday, Sep 29th)

The Patriots have now suffered their second consecutive loss, this time falling to the Jets in a disappointing 24-3 defeat. While I was expecting a stronger performance from the Patriots, it’s hard to ignore the impact of Aaron Rodgers when he’s having one of his good days. The Patriots currently find themselves at the bottom of the AFC East with a record of 1 win and 2 losses, leaving plenty of room for improvement.

On the flip side, the San Francisco 49ers are facing struggles of their own. They also sit at the bottom of their division, the NFC West, with a record of 1 win and 2 losses. Their most recent game saw them lose 23-17 to the Rams. To make matters worse, uncertainty looms around the availability of their starting quarterback, which only adds to the challenges they’re facing heading into this matchup.

If I had to make a prediction for this game, I would lean toward the 49ers. Although they haven’t been at their best lately, playing at home could give them the edge. One thing is clear: the Patriots still have a lot to work on. That being said, with the 49ers dealing with several injuries, this might be the perfect opportunity for New England to steal a win. The last time these two teams faced each other was in October 2020, when the 49ers dominated with a 33-6 victory.

My pick: The San Francisco 49ers to win this game.

SportsbookNew England Patriots Moneyline OddsSan Francisco 49ers Moneyline Odds
iBet+421-556
PowerPlay SportsTBCTBC
BetOBet+412-588
Odds were correct at the time of writing. Please check the specific site for the most up-to-date odds.

Point Spread Odds

Online Sports Betting SiteNew England Patriots OddsSan Francisco 49ers Odds
iBet(-109) +10(-109) -10
PowerPlay SportsTBCTBC
BetOBet(-114) +10(-112) -10
Odds were correct at the time of writing. Please check the specific site for the most up-to-date odds.
This is a picture of the 49ers against the Patritos for the NFL Picks week 4 article
New England Patriots vs San Francisco 49ers

New England Patriots Injury Report

  • Vederian Lowe
  • Ja’Whaun Bentley
  • Kendrick Bourne
  • Sidy Sow

San Francisco 49ers Injury Report

  • Deebo Samuel Sr.
  • Dre Greenlaw
  • Javon Hargrave
  • George Kittle
  • Christian McCaffrey
  • Brock Purdy

This ends my NFL Picks Week 4: Patriots vs 49ers article. What are your thoughts on that? Have a look at our online sportsbooks reviews If you want to learn more about the NFL’s greatest betting odds. Check DAZN Canada in order for you to view all the games you want.

About the Author

João Pedro Freitas

João Pedro Freitas has been working in online gambling since 2022, being the most recent addition to the team. He loves to write sports articles and likes to analyse all kinds of sports, especially soccer and UFC. João focuses on writing content and creating strategies to ensure that the team is up to date on all Canadian and American sports.
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