NFL Picks Week 1: Cardinals vs Bills

This is a picture of the Cardinals against the Bills for the NFL Picks week 1 article

The Buffalo Bills and the Arizona Cardinals will play their first NFL game this Sunday at Highmark Stadium. With the Bills hosting, they are clear favorites to secure a win. However, the Cardinals will certainly be aiming to pull off an upset. Who will come out on top? In this NFL Picks Week 1: Cardinals vs Bills article, I’ll try my best to tell you all the information that you need to know about this game. 

If you would like to place bets on the game check out our sports betting page. (non-Ontario).

Arizona Cardinals vs Buffalo Bills (Sunday, Sep 8th)

The Arizona Cardinals had a challenging preseason, failing to secure a single win. Their most recent defeat was a 38-12 loss to the Denver Broncos. However, it’s important to note that several of their key players were absent during these games. Looking ahead to the upcoming matchup, it is confirmed that some of their players will be sidelined, including Elijah Jones, Christian Jones, Darius Robinson, and BJ Ojulari.
On the other hand, the Buffalo Bills didn’t have an outstanding preseason either, managing only one victory—a 9-3 win against the Pittsburgh Steelers. Unfortunately, they were unable to maintain that momentum, losing their most recent game to the Carolina Panthers with a score of 31-26. For the upcoming game, it is expected that Josh Allen will play the full match, which will be crucial for the Bills. However, it will certainly feel strange to see them without star wide receiver Stefon Diggs, who recently signed with the Houston Texans.
When it comes to predicting the outcome of this game, it seems straightforward. The Bills are strong favorites, especially playing at home, and it’s hard to imagine them losing in front of their home crowd. The last time these two teams met was in November 2020, when the Cardinals narrowly edged out the Bills with a 32-30 victory.

My pick: The Buffalo Bills to win this game.

SportsbookArizona Cardinals Moneyline OddsBuffalo Bills Moneyline Odds
iBet+270-333
PowerPlay Sports+220-333
BetOBet+232-303
Odds were correct at the time of writing. Please check the specific site for the most up-to-date odds.

Point Spread Odds

Online Sports Betting SiteArizona Cardinals OddsBuffalo Bills Odds
iBet(-109) +6.5(-109) -6.5
PowerPlay Sports(-114) +6.5(-115) -6.5
BetOBet(-115) +6.5(-111) -6.5
Odds were correct at the time of writing. Please check the specific site for the most up-to-date odds.
This is a picture of the Arizona Cardinals vs Buffalo Bills for the NFL Picks week 1
Arizona Cardinals vs Buffalo Bills

This ends my NFL Picks Week 1: Cardinals vs Bills article. What are your thoughts on that? Have a look at our online sportsbooks reviews If you want to learn more about the NFL’s greatest betting odds. Check DAZN Canada in order for you to view all the games you want.

About the Author

João Pedro Freitas

João Pedro Freitas has been working in online gambling since 2022, being the most recent addition to the team. He loves to write sports articles and likes to analyse all kinds of sports, especially soccer and UFC. João focuses on writing content and creating strategies to ensure that the team is up to date on all Canadian and American sports.
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